Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956484 | 0.88 | GSK3A (0.40) | HPGDSMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL16951226 | 0.87 | NFE2L2 (0.44) | NFE2L2HPGDSMN1; SMN2KDM4ELMNA | |
| SCHEMBL16956513 | 0.85 | ALDH1A1 (0.42) | NFE2L2HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL16951406 | 0.84 | NFE2L2 (0.41) | NFE2L2HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8377299 | 0.84 | ALDH1A1 (0.58) | NFE2L2HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL16959860 | 0.83 | NPC1 (0.52) | NFE2L2HPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6632658 | 0.81 | NFE2L2 (0.61) | NFE2L2HPGDKDM4ELMNACYP1A1 | |
| SCHEMBL16958641 | 0.81 | ALDH1A1 (0.41) | NFE2L2HPGDSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL16954534 | 0.81 | HPGD (0.41) | HPGDSMN1; SMN2ALDH1A1HTTKDM4E | |
| SCHEMBL16957272 | 0.81 | ALDH1A1 (0.41) | HPGDSMN1; SMN2ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |