Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955816 | 0.86 | TSHR (0.39) | TSHRTDP1GPR35GLAALDH1A1 | |
| SCHEMBL16958951 | 0.85 | TSHR (0.38) | TSHRTDP1GPR35GLAALDH1A1 | |
| SCHEMBL16957718 | 0.81 | TSHR (0.51) | TSHRTDP1GPR35GLAALDH1A1 | |
| SCHEMBL16953062 | 0.80 | TSHR (0.53) | TSHRTDP1GPR35ALDH1A1HSPB1 | |
| SCHEMBL28150027 | 0.78 | HSPB1 (0.49) | TSHRTDP1GPR35ALDH1A1HSPB1 | |
| SCHEMBL16954017 | 0.77 | ERN1 (0.45) | TDP1GPR35ALDH1A1HSPB1HTT | |
| SCHEMBL16960779 | 0.77 | MAPT (0.48) | TSHRTDP1GPR35ALDH1A1HTT | |
| SCHEMBL16953059 | 0.76 | TDP1 (0.41) | TSHRTDP1GPR35ALDH1A1HSPB1 | |
| SCHEMBL16951102 | 0.76 | TSHR (0.46) | TSHRTDP1GPR35GLAALDH1A1 | |
| SCHEMBL21596978 | 0.76 | MAPT (0.47) | TSHRTDP1GPR35ALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |