SCHEMBL16959637

SCHEMBL16959637

Cc1cc(C2CC2)ccc1C1CC1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
HTR2C P28335 6/20 0.41
MGLL Q99685 1/20 0.39
OPRL1 P41146 4/20 0.39
ESR2 Q92731 1/20 0.38
QDPR P09417 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575326 0.90 KMO (0.43) OPRL1
SCHEMBL9399311 0.84 CYP2C9 (0.50) OPRL1ESR2
SCHEMBL23857861 0.82 MGLL (0.38) NOTUMMGLLOPRL1
SCHEMBL2884802 0.81 HTR2C (0.46) HTR2CESR2QDPR
SCHEMBL2719727 0.81 ESR2 (0.56) ESR2
SCHEMBL18773619 0.80 OPRL1 (0.37) NOTUMOPRL1
SCHEMBL9399342 0.79 OPRL1 (0.42) OPRL1
SCHEMBL29497492 0.79 HTR2C (0.38) NOTUMHTR2CMGLLQDPR
SCHEMBL15567031 0.79 CHRNB2 (0.44) NOTUMHTR2COPRL1
SCHEMBL23752805 0.78 SSTR4 (0.42) NOTUMHTR2CQDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed