Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | FOS | P01100 | 1/20 | 0.32 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957459 | 0.86 | KAT6A (0.33) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16954802 | 0.86 | SCN9A (0.46) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16950625 | 0.84 | LMNA (0.32) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16959409 | 0.81 | EPHX2 (0.39) | NR1H4F2RNR4A1NR4A2NR4A3 | |
| SCHEMBL16955748 | 0.78 | HPGD (0.43) | POLBMAPTHPGDXBP1NR1H4 | |
| SCHEMBL16959501 | 0.78 | MEN1 (0.39) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16958080 | 0.78 | POLB (0.37) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16956273 | 0.77 | PLA2G2A (0.44) | MAPT | |
| SCHEMBL16950724 | 0.77 | FFAR4 (0.41) | POLBMAPTHPGDXBP1KAT6A | |
| SCHEMBL16958541 | 0.77 | HPGD (0.40) | POLBMAPTHPGDXBP1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |