Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16960165 | 0.90 | NPC1 (0.39) | HDAC8 | |
| SCHEMBL16956767 | 0.86 | HSPA5 (0.35) | GABRA1GABRB2 | |
| SCHEMBL16955954 | 0.85 | CES2 (0.35) | GABRB2RXRARXRBRXRG | |
| SCHEMBL16957802 | 0.84 | GABRA1 (0.34) | GABRA1GABRB2HDAC8RXRARXRB | |
| SCHEMBL16959939 | 0.84 | CNR2 (0.36) | CNR1CNR2 | |
| SCHEMBL16955754 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2HDAC8RXRARXRB | |
| SCHEMBL16953460 | 0.79 | CNR1 (0.33) | RXRARXRBCNR1CNR2 | |
| SCHEMBL16953752 | 0.79 | HMGCR (0.38) | GABRA1GABRB2 | |
| SCHEMBL9935963 | 0.78 | HTR1D (0.40) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL1033820 | 0.78 | GABRA1 (0.44) | GABRA1GABRB2HDAC8RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |