Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 5/20 | 0.37 |
| ▸ | RXRB | P28702 | 5/20 | 0.37 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958822 | 0.88 | RXRA (0.40) | GABRA1GABRB2RXRARXRBMAPT | |
| SCHEMBL16953013 | 0.86 | GABRA1 (0.34) | GABRA1GABRB2MAPTCYP2C19KDM4E | |
| SCHEMBL16962958 | 0.86 | ACHE (0.35) | GABRA1GABRB2CYP2C19ACHEPTPN7 | |
| SCHEMBL16956521 | 0.86 | NOTUM (0.37) | GABRA1GABRB2MEN1KMT2ACYP2C19 | |
| SCHEMBL16956767 | 0.85 | HSPA5 (0.35) | GABRA1GABRB2CYP2C19ACHEPTPN7 | |
| SCHEMBL16955876 | 0.83 | CA1 (0.39) | GABRA1GABRB2MEN1KMT2AMAPT | |
| SCHEMBL16961626 | 0.83 | CYP1A2 (0.33) | GABRA1GABRB2RXRARARARARB | |
| SCHEMBL16959870 | 0.82 | GABRA1 (0.31) | GABRA1GABRB2RXRARXRBRXRG | |
| SCHEMBL16960119 | 0.82 | KIF11 (0.37) | GABRA1GABRB2MAPT | |
| SCHEMBL16953752 | 0.80 | HMGCR (0.38) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |