Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ACP3 | P15309 | 3/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827175 | 1.00 | MEN1 (0.59) | MEN1KMT2AACP3MEP1BSMN1; SMN2 | |
| SCHEMBL19248981 | 1.00 | MEN1 (0.59) | MEN1KMT2AACP3MEP1BSMN1; SMN2 | |
| SCHEMBL6243334 | 0.90 | ALDH1A1 (0.55) | MEN1KMT2AACP3MEP1B | |
| SCHEMBL16664378 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ACYP1A2 | |
| SCHEMBL2485602 | 0.88 | ALDH1A1 (0.50) | MEN1KMT2ACYP1A2 | |
| SCHEMBL2485050 | 0.88 | SMN1; SMN2 (0.59) | MEN1KMT2AMEP1BSMN1; SMN2CNR2 | |
| SCHEMBL28387051 | 0.88 | LMNA (0.56) | MEN1KMT2AMEP1BSMN1; SMN2 | |
| SCHEMBL11350168 | 0.88 | CYP1A2 (0.56) | MEN1KMT2ASMN1; SMN2GABRB1GABRB2 | |
| SCHEMBL4427598 | 0.88 | CNR2 (0.51) | MEN1KMT2AACP3MEP1BCNR2 | |
| SCHEMBL29228705 | 0.88 | ATM (0.52) | MEN1KMT2ASMN1; SMN2GABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102264734-B | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMA SPA | 2015-06-17 | — | — | CN | claimed |
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | claimed |
| US-8455646-B2 | Alkaloid aminoester derivatives and medicinal composition thereof | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-06-04 | — | — | US | claimed |
| CN-102264734-A | Alkaloid aminoester derivatives and medicinal composition thereof | — | 2011-11-30 | — | — | CN | claimed |
| CN-102070576-A | 1-indanone-3-acetic acid compound as well as preparation method and application of 1-indanone-3-acetic acid compound | UNIV SICHUAN | 2011-05-25 | — | — | CN | claimed |
| CN-101993426-A | 3-aryl glutaric acid mono-amide compound as well as preparation method and application thereof | UNIV SICHUAN | 2011-03-30 | — | — | CN | claimed |
| US-20100173880-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-08 | — | — | US | claimed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | claimed |
| JP-57064655-A | — | — | None | — | — | JP | disclosed |
| CN-118026886-A | Synthesis method of various functionalized beta-amino acid esters | 国科大杭州高等研究院 | 2024-05-14 | — | — | CN | disclosed |
| CN-110683960-A | Synthesis method of (R) -3-aminobutanol | 台州达辰药业有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-107840859-A | The cobalt complex and synthetic method that a kind of toluene and 2,2 ' bipyridyls are constructed | 桂林理工大学 | 2018-03-27 | — | — | CN | disclosed |
| CN-107057078-A | Novel magnetic polymeric material and synthetic method that a kind of toluene and 4,4 ' bipyridyls are constructed | 桂林理工大学 | 2017-08-18 | — | — | CN | disclosed |
| CN-107056847-A | Novel magnetic materials and synthetic method that a kind of toluene and 4,4 ' bipyridyls are constructed | 桂林理工大学 | 2017-08-18 | — | — | CN | disclosed |
| WO-2010072338-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-07-01 | — | — | WO | disclosed |
| CN-1846696-A | Method for producing enantiomer-free n-methyl-n- [(1s)-1-phenyl- 2-((3s)- 3-hydroxypyrrolidine- 1-yl)ethyl]- 2,2-diphenyl acetamide | MERCK PATENT GMBH (DE) | 2006-10-18 | — | — | CN | disclosed |
| US-4502883-A | CONTAINING CHLORINE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1985-03-05 | — | — | US | disclosed |
| JP-S5764655-A | NOVEL BENZOYLAMINOPHENYLCARBOXYLIC ACID DERIVATIVE, ITS PREPARATION, AND DRUG COMPOSITION COMPRISING IT | NIPPON ZOKI PHARMACEUT CO LTD | 1982-04-19 | — | — | JP | disclosed |
| US-4218475-A | ANTICHOLESTEROL AGENTS | THE DOW CHEMICAL COMPANY (US) | 1980-08-19 | — | — | US | disclosed |
| US-3957850-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | BOUCHARA EMILE | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173880-A1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHRM3, CHRM1, CHRNG | MEN1 4121/4885KMT2A 1874/4885ACP3 4235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.