SCHEMBL29228705

SCHEMBL29228705

O=C(O)C(NCc1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GABRB1 P18505 1/20 0.52
GABRB2 P47870 1/20 0.52
CNR2 P34972 2/20 0.51
AKT1 P31749 2/20 0.50
CYP2D6 P10635 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP1A2 P05177 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
UTS2R Q9UKP6 2/20 0.46
CNR1 P21554 1/20 0.46
PLAAT3 P53816 1/20 0.46
PLAAT5 Q96KN8 1/20 0.46
PLAAT2 Q9NWW9 1/20 0.46
PLAAT4 Q9UL19 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11350168 0.94 CYP1A2 (0.56) ATML3MBTL1GABRB1GABRB2CNR2
SCHEMBL19248981 0.88 MEN1 (0.59) GABRB1GABRB2CNR2CYP1A2MEN1
SCHEMBL27827175 0.88 MEN1 (0.59) GABRB1GABRB2CNR2CYP1A2MEN1
SCHEMBL1696017 0.88 MEN1 (0.59) GABRB1GABRB2CNR2CYP1A2MEN1
SCHEMBL5224347 0.84 CNR2 (0.51) CNR2CYP2D6CYP2C19CYP2C9CYP1A2
SCHEMBL4427598 0.84 CNR2 (0.51) CNR2CYP2D6CYP2C19CYP2C9CYP1A2
SCHEMBL4237244 0.82 CYP1A2 (0.51) GABRB1GABRB2CYP2D6CYP2C19CYP1A2
SCHEMBL10572282 0.79 KMT2A (0.70) GABRB1GABRB2CYP2D6CYP2C19CYP2C9
SCHEMBL6462875 0.79 GABRB1 (0.51) ATML3MBTL1GABRB1GABRB2CNR2
SCHEMBL6243334 0.79 ALDH1A1 (0.55) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026886-A Synthesis method of various functionalized beta-amino acid esters 国科大杭州高等研究院 2024-05-14 CN disclosed