Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460479 | 0.84 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16953864 | 0.79 | LMNA (0.37) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16959194 | 0.77 | — | — | |
| SCHEMBL8425831 | 0.77 | CYP1A2 (0.47) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16961008 | 0.77 | LMNA (0.39) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL24312388 | 0.75 | KDM4E (0.38) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16960044 | 0.75 | ABCB1 (0.40) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL16960042 | 0.75 | KDM4E (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL95282 | 0.72 | — | — | |
| SCHEMBL42242 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |