Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195589 | 0.79 | ALDH1A1 (0.42) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL16953866 | 0.79 | GRM5 (0.41) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL16961006 | 0.79 | SMN1; SMN2 (0.38) | LMNANPC1RAB9AMAPTKMT2A | |
| SCHEMBL21859573 | 0.78 | L3MBTL1 (0.40) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL16950519 | 0.77 | NPC1 (0.37) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL16950516 | 0.77 | LMNA (0.35) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL16957446 | 0.75 | APOBEC3G (0.41) | LMNANPSR1NPC1RAB9AMAPT | |
| SCHEMBL796952 | 0.75 | ALDH1A1 (0.45) | LMNANPSR1MAPTKMT2AMEN1 | |
| SCHEMBL16952456 | 0.75 | SCN4A (0.41) | LMNAKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16957443 | 0.74 | NPC1 (0.40) | LMNANPSR1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |