Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954341 | 0.83 | TSHR (0.34) | TSHRCES2CES1TAS1R3TAS1R1 | |
| SCHEMBL16961076 | 0.81 | KMT2A (0.37) | GAAKMT2ACES2CES1ALDH1A1 | |
| SCHEMBL16951918 | 0.81 | TSHR (0.48) | TSHRKMT2AMEN1TAS1R3TAS1R1 | |
| SCHEMBL16954702 | 0.81 | NOTUM (0.40) | TSHRGAAKMT2AMEN1CES2 | |
| SCHEMBL16956745 | 0.81 | ALDH1A1 (0.42) | KMT2AMEN1NOTUMTAS1R3TAS1R1 | |
| SCHEMBL16955031 | 0.81 | ALDH1A1 (0.32) | GAAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16952577 | 0.79 | MEN1 (0.35) | TSHRGAAKMT2AMEN1TDP1 | |
| SCHEMBL16961032 | 0.79 | MEN1 (0.35) | KMT2AMEN1RORCALDH1A1SMN1; SMN2 | |
| SCHEMBL16961198 | 0.78 | TSHR (0.39) | TSHRKMT2AMEN1CES2CES1 | |
| SCHEMBL16960985 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| US-8968701-B2 | Usage of low to medium-pressure liquid chromatography for the purification of radiotracers | PIRAMAL IMAGING SA (CH) | 2015-03-03 | — | — | US | disclosed |