Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.32 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962916 | 0.82 | PDE5A (0.35) | KMT2APDE5APDE1APDE1BPDE1C | |
| SCHEMBL16961076 | 0.82 | KMT2A (0.37) | KMT2AALDH1A1HPGDKDM4ENPC1 | |
| SCHEMBL16955031 | 0.82 | ALDH1A1 (0.32) | KMT2AALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL16952726 | 0.82 | TRPA1 (0.43) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16952577 | 0.81 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16953858 | 0.80 | KAT6A (0.40) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL16961777 | 0.79 | TSHR (0.33) | MEN1KMT2AALDH1A1RORCSMN1; SMN2 | |
| SCHEMBL16960985 | 0.79 | — | — | |
| SCHEMBL16957898 | 0.78 | F2R (0.34) | KMT2AALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL16951114 | 0.78 | GABRA1 (0.55) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |