Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951364 | 0.86 | CYP11B1 (0.40) | NOTUMKAT6ACYP11B1CYP11B2SLC6A2 | |
| SCHEMBL16956745 | 0.84 | ALDH1A1 (0.42) | NOTUMMEN1KMT2AALDH1A1TAS1R3 | |
| SCHEMBL16951918 | 0.84 | TSHR (0.48) | TSHRP2RX7MEN1KMT2AALDH1A1 | |
| SCHEMBL16955639 | 0.81 | KAT6A (0.41) | NOTUMKAT6ACYP11B1CYP11B2SLC6A2 | |
| SCHEMBL16961777 | 0.81 | TSHR (0.33) | NOTUMTSHRGAACES2CES1 | |
| SCHEMBL16961987 | 0.79 | GAA (0.40) | TSHRGAAMEN1KMT2ATDP1 | |
| SCHEMBL16957491 | 0.79 | CES2 (0.54) | KAT6AGAACES2CES1KMT2A | |
| SCHEMBL16952864 | 0.78 | NPC1 (0.33) | NOTUMTSHRGAACES2CES1 | |
| SCHEMBL16961294 | 0.78 | NOTUM (0.40) | NOTUMTSHRKMT2ATDP1ALDH1A1 | |
| SCHEMBL3612002 | 0.78 | KAT6A (0.46) | NOTUMKAT6ACYP11B1CYP11B2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |