Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435768 | 0.82 | TRPV4 (0.56) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL2702726 | 0.82 | RORC (0.50) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL16957724 | 0.82 | MAPT (0.46) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL1547765 | 0.75 | TDP1 (0.56) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL2611833 | 0.73 | MAPT (0.75) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL3786617 | 0.73 | NQO1 (0.52) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL12412421 | 0.73 | CYP2C19 (0.64) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL2220583 | 0.72 | RORC (0.54) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL12300310 | 0.72 | MAPT (0.54) | MAPTRAB9AL3MBTL1RORCATM | |
| SCHEMBL3993850 | 0.72 | TSHR (0.58) | MAPTRAB9AL3MBTL1RORCATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |