Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236752 | 0.79 | SMN1; SMN2 (0.37) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL8847437 | 0.79 | MEN1 (0.42) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL8847707 | 0.77 | TDP1 (0.37) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL11772759 | 0.70 | LMNA (0.38) | KDM4EHTTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7266968 | 0.65 | NSD3 (0.42) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL8631734 | 0.65 | KMT2A (0.42) | MEN1KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11405385 | 0.64 | MEN1 (0.63) | MEN1KMT2AALDH1A1KDM4ERAB9A | |
| SCHEMBL5005046 | 0.64 | MEN1 (0.69) | MEN1KMT2AALDH1A1KDM4EHTT | |
| SCHEMBL13325667 | 0.64 | NPC1 (0.62) | MEN1KMT2AHTTRAB9ANPC1 | |
| SCHEMBL10205951 | 0.64 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011142381-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | FUJITA TAKASHI (JP) | 2011-11-17 | — | — | WO | disclosed |