Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961822 | 0.86 | HPGD (0.47) | HPGDARKMT2AMEN1ALDH1A1 | |
| SCHEMBL16957272 | 0.85 | ALDH1A1 (0.41) | HPGDARKMT2AALDH1A1HTT | |
| SCHEMBL16956139 | 0.83 | HPGD (0.41) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL15077481 | 0.83 | ALDH1A1 (0.55) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL16955133 | 0.81 | HTR1B (0.40) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL16952922 | 0.80 | MCHR1 (0.39) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL16962844 | 0.80 | MCHR1 (0.39) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL16959262 | 0.80 | NPC1 (0.41) | HPGDARMCHR1KMT2AMEN1 | |
| SCHEMBL16951226 | 0.79 | NFE2L2 (0.44) | HPGDMCHR1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16950721 | 0.79 | PTGES (0.41) | HPGDARMCHR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |