Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953460 | 0.90 | CNR1 (0.33) | RXRARXRBTRPA1PTGS2ALDH1A1 | |
| SCHEMBL16953075 | 0.87 | SLC7A5 (0.37) | RXRARXRBPTGS2 | |
| SCHEMBL16957567 | 0.87 | MAPT (0.33) | RXRARXRBSMN1; SMN2 | |
| SCHEMBL16952013 | 0.87 | HPGD (0.43) | PTGS2ALDH1A1 | |
| SCHEMBL16959004 | 0.87 | OPRM1 (0.33) | RXRARXRB | |
| SCHEMBL16958949 | 0.86 | RXRA (0.30) | RXRARXRB | |
| SCHEMBL16960999 | 0.86 | CYP4F2 (0.35) | RXRARXRBTRPA1 | |
| SCHEMBL16956690 | 0.82 | PTGS2 (0.37) | PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16956767 | 0.82 | HSPA5 (0.35) | TRPA1HSPA5 | |
| SCHEMBL16957394 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |