SCHEMBL16962913

SCHEMBL16962913

C[C](CO)c1cc(Cl)ccc1OC(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.41
RORC P51449 1/20 0.40
ALDH1A1 P00352 2/20 0.40
SLC9A1 P19634 1/20 0.39
TSHR P16473 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
LMNA P02545 1/20 0.37
KMT2A Q03164 1/20 0.37
GBA1 P04062 1/20 0.37
MAPT P10636 1/20 0.36
HMOX1 P09601 1/20 0.36
TSPO P30536 1/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16958906 0.86 KMT2A (0.40) ALDH1A1TSHRSMN1; SMN2LMNAKMT2A
SCHEMBL16953749 0.83 RORC (0.44) CSNK2A1RORCALDH1A1SLC9A1TSHR
SCHEMBL16955567 0.82 IDO1 (0.45) CSNK2A1RORCALDH1A1TSHRHTR2B
SCHEMBL3045049 0.81 KMT2A (0.52) RORCALDH1A1SLC9A1TSHRHTR2A
SCHEMBL16959647 0.81 LMNA (0.54) ALDH1A1TSHRLMNAKMT2AMAPT
SCHEMBL16954021 0.81 IRAK4 (0.39) CSNK2A1RORCALDH1A1SMN1; SMN2KMT2A
SCHEMBL16957959 0.81 PTGDR2 (0.44) CSNK2A1RORCALDH1A1TSHRSMN1; SMN2
SCHEMBL16955956 0.79 NPSR1 (0.41) ALDH1A1HTR2AKMT2AMAPTCYP3A4
SCHEMBL16960391 0.79 TSHR (0.49) RORCSLC9A1TSHRHTR2AHTR2C
SCHEMBL16950477 0.77 SLC6A9 (0.41) IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed