Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.49 |
| ▸ | ARG2 | P78540 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3676543 | 0.76 | ARG1 (0.54) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3675366 | 0.76 | ARG1 (0.54) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28207275 | 0.76 | ARG1 (0.54) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1359692 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30085352 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1359695 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28174553 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30593437 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5442859 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL28206792 | 0.75 | ARG1 (0.53) | ARG1ARG2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540620-B2 | Methods and compositions for modulating G-alpha-Q signaling | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2017-01-10 | — | — | US | disclosed |
| US-20150218538-A1 | Methods and Compositions for Modulating G-Alpha-Q Signaling | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-08-06 | — | — | US | disclosed |