Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 3/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 4/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169678 | 1.00 | SLC5A2 (0.36) | SLC5A2SLC5A1SLC6A11SLC6A1KIF11 | |
| SCHEMBL6880054 | 1.00 | SLC5A2 (0.36) | SLC5A2SLC5A1SLC6A11SLC6A1KIF11 | |
| SCHEMBL132699 | 0.87 | SLC6A11 (0.38) | SLC6A11SLC6A1KIF11HTTLMNA | |
| SCHEMBL135522 | 0.84 | SLC6A11 (0.35) | SLC5A2SLC5A1SLC6A11SLC6A1LMNA | |
| SCHEMBL169481 | 0.78 | EGFR (0.35) | SLC5A2SLC5A1SLC6A11SLC6A1KDM4E | |
| SCHEMBL169480 | 0.78 | EGFR (0.35) | SLC5A2SLC5A1SLC6A11SLC6A1KDM4E | |
| SCHEMBL131200 | 0.78 | — | — | |
| SCHEMBL131201 | 0.78 | — | — | |
| SCHEMBL133759 | 0.75 | SLC6A1 (0.33) | SLC6A11SLC6A1HTTLMNAMAPT | |
| SCHEMBL6277830 | 0.75 | SLC6A1 (0.33) | SLC6A11SLC6A1HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446412-B1 | NOVEL LNA COMPOSITIONS AND USES THEREOF | EXIQON AS (DK) | 2012-03-07 | — | — | EP | disclosed |
| EP-1556510-A2 | OLIGONUCLEOTIDE ANALOGUES FOR DETECTING AND ANALYZING NUCLEIC ACIDS | Exiqon A/S (DK) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004035819-A2 | OLIGONUCLEOTIDE ANALOGUES FOR DETECTING AND ANALYZING NUCLEIC ACIDS | EXIQON A/S (DK) | 2004-04-29 | — | — | WO | disclosed |