Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16985194 | 0.95 | HTR3A (0.37) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL18892420 | 0.92 | SLC6A4 (0.31) | HTR3ASLC6A4 | |
| SCHEMBL16986035 | 0.89 | HTR3A (0.39) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL16970585 | 0.88 | HTR3A (0.41) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL18884169 | 0.87 | SLC6A4 (0.31) | HTR3ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14013423 | 0.86 | MEN1 (0.43) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL14013342 | 0.85 | HTR3A (0.44) | HTR3AP2RY6ITPR1CA12CA1 | |
| Hydrochloric Acid SCHEMBL3997760 | 0.85 | MEN1 (0.42) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL29348181 | 0.85 | ITPR1 (0.42) | HTR3AP2RY6ITPR1CA12CA1 | |
| SCHEMBL14013355 | 0.85 | HTR3A (0.44) | HTR3AP2RY6ITPR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2019-04-09 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-20170145214-A1 | FLUOROGENIC PH-SENSITIVE DYES AND THEIR METHODS OF USE (II) | Life Technologies Corporation | 2017-05-25 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-9599622-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | Life Technologies Corporation (US) | 2017-03-21 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
| US-20150218379-A1 | Fluorogenic pH-Sensitive Dyes and Their Methods of Use (II) | Life Technologies Corporation | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253185-B2 | Fluorogenic pH-sensitive dyes and their methods of use (II) | ALPG, XDH, ASAH2 | HTR3A 1591/4885P2RY6 918/4885ITPR1 2647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.