Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Arginine SCHEMBL16970951 | 1.00 | CYP1A2 (0.50) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL3487127 | 0.93 | PTGS1 (0.52) | CYP1A2GSRPTGS1SLC7A11OTC | |
| Arginine SCHEMBL4749671 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL6803653 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL578156 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL573880 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL578155 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL3487131 | 0.93 | PTGS1 (0.52) | CYP1A2GSRPTGS1SLC7A11OTC | |
| Arginine SCHEMBL577728 | 0.93 | GSR (0.58) | CYP1A2GSRGRM8GRM6GRIN2D | |
| Arginine SCHEMBL5586520 | 0.93 | PTGS1 (0.52) | CYP1A2GSRPTGS1SLC7A11OTC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4172275-B1 | TIO2-FREE PIGMENT | SUN CHEMICAL CORP (US) | 2024-02-07 | — | — | EP | claimed |
| US-20230212400-A1 | TiO2-FREE PIGMENT | SUN CHEMICAL CORPORATION | 2023-07-06 | — | — | US | claimed |
| EP-4172275-A1 | TIO2-FREE PIGMENT | Sun Chemical Corporation (US) | 2023-05-03 | — | — | EP | claimed |
| CN-212356645-U | Separation membrane for groundwater pollution remediation | 中新瑞美(天津)环保科技有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-111137952-A | Preparation method of separation membrane for groundwater pollution remediation | 中新瑞美(天津)环保科技有限公司 | 2020-05-12 | — | — | CN | claimed |
| CN-108444963-B | Method for detecting glutathione and application of gold-sulfur compound | 中国人民解放军国防科技大学 | 2019-09-10 | — | — | CN | claimed |
| CN-108444963-A | Method for detecting glutathione and application of gold-sulfur compound | 中国人民解放军国防科技大学 | 2018-08-24 | — | — | CN | claimed |
| EP-4172275-B1 | TIO2-FREE PIGMENT | SUN CHEMICAL CORP (US) | 2024-02-07 | — | — | EP | disclosed |
| EP-3102639-B1 | SURFACE-TREATED CALCIUM CARBONATE, METHODS FOR MAKING THE SAME, AND COMPOSITIONS INCLUDING THE SAME | SENSIENT COLORS LLC (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230212400-A1 | TiO2-FREE PIGMENT | SUN CHEMICAL CORPORATION | 2023-07-06 | — | — | US | disclosed |
| EP-4172275-A1 | TIO2-FREE PIGMENT | Sun Chemical Corporation (US) | 2023-05-03 | — | — | EP | disclosed |
| CN-212356645-U | Separation membrane for groundwater pollution remediation | 中新瑞美(天津)环保科技有限公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-111137952-A | Preparation method of separation membrane for groundwater pollution remediation | 中新瑞美(天津)环保科技有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-108444963-B | Method for detecting glutathione and application of gold-sulfur compound | 中国人民解放军国防科技大学 | 2019-09-10 | — | — | CN | disclosed |
| CN-108444963-A | Method for detecting glutathione and application of gold-sulfur compound | 中国人民解放军国防科技大学 | 2018-08-24 | — | — | CN | disclosed |
| EP-3102639-A1 | SURFACE-TREATED CALCIUM CARBONATE, METHODS FOR MAKING THE SAME, AND COMPOSITIONS INCLUDING THE SAME | Sensient Colors LLC (US) | 2016-12-14 | — | — | EP | disclosed |
| US-9328244-B2 | Surface-treated calcium carbonate, methods for making the same, and compositions including the same | SENSIENT COLORS LLC (US) | 2016-05-03 | — | — | US | disclosed |
| WO-2015120007-A1 | SURFACE-TREATED CALCIUM CARBONATE, METHODS FOR MAKING THE SAME, AND COMPOSITIONS INCLUDING THE SAME | SENSIENT COLORS LLC (US) | 2015-08-13 | — | — | WO | disclosed |
| US-20150218381-A1 | Surface-Treated Calcium Carbonate, Methods for Making the Same, and Compositions Including the Same | SENSIENT COLORS LLC | 2015-08-06 | — | — | US | disclosed |