Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28189341 | 0.81 | TP53 (0.36) | CTRB1TSHR | |
| SCHEMBL2477172 | 0.81 | FOLH1 (0.42) | FOLH1KDM4EHTTTSHR | |
| SCHEMBL2166841 | 0.76 | CYP1A2 (0.41) | TSHR | |
| SCHEMBL9777592 | 0.74 | FOLH1 (0.46) | FOLH1HTT | |
| SCHEMBL2168812 | 0.73 | CYP1A2 (0.46) | HTTTSHR | |
| SCHEMBL29852176 | 0.71 | FOLH1 (0.51) | FOLH1KDM4EHTT | |
| SCHEMBL10552613 | 0.71 | CYP1A2 (0.53) | HTTTSHR | |
| SCHEMBL2805843 | 0.71 | TSHR (0.39) | FOLH1TSHR | |
| SCHEMBL7352473 | 0.71 | FASN (0.43) | CTRB1 | |
| SCHEMBL28762173 | 0.71 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010395-A1 | POLYURETHANE FOAM COMPOSITION COMPRISING AN AROMATIC POLYESTER POLYOL COMPOUND AND PRODUCTS MADE THEREFROM | Huntsman International LLC (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-4010394-A1 | POLYESTER POLYOL COMPRISING AN IMIDE MOIETY AND METHODS OF MANUFACTURE THEREOF | Huntsman International LLC (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-114341222-A | Polyurethane foam compositions containing aromatic polyester polyol compounds and products made therefrom | 亨斯迈国际有限责任公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114286831-A | Polyester polyol containing imide moiety and method for preparing the same | 亨斯迈国际有限责任公司 | 2022-04-05 | — | — | CN | disclosed |
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | disclosed |
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2017-10-26 | — | — | US | disclosed |
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732112-B2 | Synthesis of 2′,3′-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization | Life Technologies Corporation (US) | 2017-08-15 | — | — | US | disclosed |
| WO-2011150277-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011150277-A2 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | Life Technologies Corporation (US) | 2011-12-01 | — | — | WO | disclosed |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2011-12-01 | — | — | US | disclosed |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | Life Technologies Corporation (US) | 2011-12-01 | — | — | US | disclosed |
| EP-0214853-B1 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING & MFG (US) | 1994-11-30 | — | — | EP | disclosed |
| US-4883864-A | COUPLED AND FREE AMINE GROUPS CAPPED WITH UREA OR AMIDE GROUPS, EYE SURGERY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4851513-A | Viscoelastic collagen solution for opthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-25 | — | — | US | disclosed |
| US-4713446-A | COLLAGEN COUPLED TO CARBONYL OR SULFONYL GROUPS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-12-15 | — | — | US | disclosed |
| EP-0214853-A2 | Viscoelastic collagen solution for ophthalmic use and method of preparation | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4085260-A | Powder coating compositions with hydroxy containing acrylic copolymers-I and carboxylic acid or anhydride crosslinking agent | FORD MOTOR COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305954-A1 | SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION | DCTD, MTAP, RNGTT | FOLH1 686/4885KDM4E 2128/4885HTT 2557/4885 |
| US-20110294122-A1 | Synthesis of 2', 3'-Dideoxynucleosides for Automated DNA Synthesis and Pyrophosphorolysis Activated Polymerization | DCTD, MTAP, RNGTT | FOLH1 686/4885KDM4E 2128/4885HTT 2557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.