SCHEMBL1697201

SCHEMBL1697201

CC(=O)CCCC(=O)CCc1ccc(O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.54
IAPP P10997 2/20 0.49
ALDH1A1 P00352 3/20 0.48
CYP19A1 P11511 2/20 0.47
KDM4E B2RXH2 3/20 0.47
F13A1 P00488 1/20 0.47
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ESR1 P03372 4/20 0.45
ESR2 Q92731 1/20 0.45
LMNA P02545 2/20 0.45
TP53 P04637 2/20 0.45
CYP3A4 P08684 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
SLC16A3 O15427 1/20 0.45
TTR P02766 1/20 0.45
CYP1A2 P05177 1/20 0.45
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106915 0.85 ESR1 (0.53) TRPV1ALDH1A1KDM4EF13A1ESR1
Raspberryketone SCHEMBL43308 0.85 ALDH1A1 (0.65) ALDH1A1CYP19A1KDM4EF13A1MEN1
SCHEMBL8108885 0.84 ESR1 (0.62) TRPV1IAPPALDH1A1CYP19A1KDM4E
SCHEMBL27921443 0.84 IAPP (0.68) TRPV1IAPPALDH1A1KDM4EESR1
SCHEMBL2565118 0.83 ACHE (0.57) TRPV1ALDH1A1KDM4EF13A1ESR1
Raspberryketone SCHEMBL30530334 0.82 ALDH1A1 (0.58) ALDH1A1CYP19A1KDM4EF13A1MEN1
SCHEMBL4383632 0.81 ACHE (0.60) TRPV1ALDH1A1KDM4EF13A1ESR1
SCHEMBL9834899 0.81 ACHE (0.60) TRPV1ALDH1A1KDM4EF13A1ESR1
SCHEMBL1645396 0.81 KDM4E (0.55) TRPV1ALDH1A1CYP19A1KDM4EF13A1
SCHEMBL5537458 0.81 ACHE (0.60) TRPV1ALDH1A1KDM4EF13A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3274437-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS The Procter and Gamble Company (US) 2018-01-31 EP disclosed
WO-2016154410-A1 FABRIC CARE COMPOSITIONS COMPRISING ORGANOSILOXANE POLYMERS THE PROCTER & GAMBLE COMPANY (US) 2016-09-29 WO disclosed
EP-2588587-A1 RINSE ADDED AMINOSILICONE CONTAINING COMPOSITIONS AND METHODS OF USING SAME The Procter and Gamble Company (US) 2013-05-08 EP disclosed
WO-2012003192-A1 RINSE ADDED AMINOSILICONE CONTAINING COMPOSITIONS AND METHODS OF USING SAME THE PROCTER & GAMBLE COMPANY (US) 2012-01-05 WO disclosed