SCHEMBL6239265

SCHEMBL6239265

NC(=O)C[C@H](N)C(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 7/20 0.41
GRIK2 Q13002 4/20 0.41
ALOX15 P16050 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41
KMT2A Q03164 1/20 0.41
GRM1 Q13255 1/20 0.39
GRM2 Q14416 1/20 0.39
GRIA4 P48058 3/20 0.39
GRIK3 Q13003 3/20 0.39
GRIK5 Q16478 3/20 0.39
SLC7A5 Q01650 1/20 0.38
PTGS1 P23219 1/20 0.35
SLC7A11 Q9UPY5 1/20 0.35
GGT1 P19440 4/20 0.35
SLC1A1 P43005 4/20 0.35
SLC1A3 P43003 2/20 0.34
SLC1A2 P43004 2/20 0.34
GRIA2 P42262 2/20 0.34
GRIA1 P42261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867143 0.90 ALOX15 (0.31) ALOX15BLMPMP22KMT2A
SCHEMBL9701317 0.90 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL17222477 0.90 GRIK1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL16054489 0.87 ALOX15 (0.43) GRIK1GRIK2ALOX15BLMPMP22
SCHEMBL7614969 0.84 KMT2A (0.55) GRIK1GRIK2ALOX15BLMPMP22
SCHEMBL7998071 0.84 ALOX15 (0.60) GRIK1GRIK2ALOX15BLMPMP22
SCHEMBL16466602 0.82 SLC1A1 (0.45) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL5639011 0.82 ALOX15 (0.35) ALOX15BLMPMP22KMT2A
SCHEMBL16972731 0.81 SLC7A5 (0.64) GRIK1GRIK2GRM1GRM2GRIA4
SCHEMBL11061010 0.81 ALOX15 (0.36) GRIK1GRIK2ALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1600852-A Mutations responsible for attenuation in measles virus or human respiratory syncytial virus subgroup B AMERICAN CYANAMID CO (US) 2005-03-30 CN claimed
CN-1294628-A Mutations causing attenuation of measles virus or human respiratory syncytial virus subgroup B AMERICAN CYANAMID CO (US) 2001-05-09 CN claimed
US-20240150752-A1 METHODS AND COMPOSITIONS FOR MUTAGENESIS SCREENING IN MAMMALIAN CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-05-09 US disclosed
US-20240141330-A1 METHODS AND COMPOSITIONS FOR MUTAGENESIS SCREENING IN MAMMALIAN CELLS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-05-02 US disclosed
CN-117157049-A ATP synthase inhibitor-cosmetic and therapeutic use 迈克尔·大卫·福雷斯特 2023-12-01 CN disclosed
CN-113943818-A SNP marker locus related to horse plateau hypoxia adaptability and application thereof 佛山科学技术学院 2022-01-18 CN disclosed
CN-111983238-A Probe for dynamically detecting protein O-GlcNAc glycosylation and preparation method and application thereof 中南大学湘雅医院 2020-11-24 CN disclosed
CN-104271595-B Proteins toxic to hemipteran insect species 孟山都技术公司 2018-09-18 CN disclosed
CN-104204201-B For the method for the solubility for improving alkali protease 花王株式会社 2017-12-12 CN disclosed
CN-107074965-A Specifically bind microtubule associated protein TAU antibody and antigen-binding fragment 扬森疫苗与预防公司 2017-08-18 CN disclosed
CN-107074935-A Specifically bind microtubule associated protein TAU antibody and antigen-binding fragment 扬森疫苗与预防公司 2017-08-18 CN disclosed
EP-1063285-B1 Process for the preparation of a beer-type beverage CERESTAR HOLDING BV (NL) 2004-02-04 EP disclosed
US-6448386-B2 GENETIC ENGINEERING AVENTIS PASTEUR LIMITED (CA) 2002-09-10 US disclosed
US-6440425-B1 SPECIFICALLY, M. CATARRHALIS STRAIN 4223; VECTORS; VACCINES AGAINST INFECTIONS SUCH AS OTITIS MEDIA AVENTIS PASTEUR LIMITED (CA) 2002-08-27 US disclosed
EP-1063285-A1 Process for the preparation of a beer-type beverage CERESTAR HOLDING B.V. (NL) 2000-12-27 EP disclosed
WO-1996034960-A1 HIGH MOLECULAR WEIGHT MAJOR OUTER MEMBRANE PROTEIN OF MORAXELLA CONNAUGHT LABORATORIES LIMITED (CA) 1996-11-07 WO disclosed
EP-0580737-A4 HETERODIMERIC RECEPTOR LIBRARIES USING PHAGEMIDS SCRIPPS RESEARCH INST (US) 1996-04-24 EP disclosed
EP-0580737-A1 HETERODIMERIC RECEPTOR LIBRARIES USING PHAGEMIDS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-02-02 EP disclosed
EP-0465122-A1 Process of making 2,5-diaryl tetrahydrofurans and analogs thereof useful as paf antagonists MERCK & CO. INC. (US) 1992-01-08 EP disclosed
US-5001112-A Antitumor antibiotic kedarcidin BRISTOL-MYERS COMPANY (US) 1991-03-19 US disclosed