SCHEMBL5707690

SCHEMBL5707690

C[C@H](N)C(=O)OC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.48
GRIK1 P39086 12/20 0.47
GRIK2 Q13002 7/20 0.47
GRIA4 P48058 3/20 0.44
GRIK3 Q13003 3/20 0.44
GRIK5 Q16478 3/20 0.44
SLC1A3 P43003 5/20 0.44
SLC1A2 P43004 5/20 0.44
SLC1A1 P43005 5/20 0.44
GRIA2 P42262 2/20 0.43
GRIA1 P42261 1/20 0.43
GRM1 Q13255 1/20 0.41
GRM2 Q14416 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL464909 0.86 GRIK1 (0.31) SLC7A5GRIK1GRIK2
SCHEMBL29291859 0.84 SLC1A1 (0.42) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL9701317 0.83 GRIK1 (0.45) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL17222477 0.83 GRIK1 (0.45) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL28242874 0.83 SLC7A5 (0.44) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL8439242 0.83 SLC7A5 (0.44) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL16972731 0.83 SLC7A5 (0.64) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL21682803 0.82 SLC7A5 (0.47) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL1444867 0.81 SLC1A1 (0.50) SLC7A5GRIK1GRIK2GRIA4GRIK3
SCHEMBL5165368 0.80 GRIK1 (0.42) SLC7A5GRIK1GRIK2GRIA4GRIK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101918834-A Calibrator/control for simultaneous assay of proteins capable of complexing with one another ORTHO CLINICAL DIAGNOSTICS INC 2010-12-15 CN claimed
EP-1292615-B1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH CORP (US) 2006-10-25 EP claimed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US claimed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US claimed
EP-0210257-A4 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS. HURWITZ CHARLES (US) 1988-01-20 EP claimed
EP-0210257-A1 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS HURWITZ, Charles (US) 1987-02-04 EP claimed
WO-1986004588-A1 PROTEIN WHICH IS CHARACTERISTIC OF RHEUMATOID ARTHRITIS HURWITZ CHARLES (US) 1986-08-14 WO claimed
CN-110291196-A Thermostable reverse transcriptase mutants 宝生物工程株式会社 2019-09-27 CN disclosed
CN-107108729-A Antibodies comprising an ion concentration-dependent antigen-binding domain, FC region variants, IL-8-binding antibodies, and uses thereof 中外制药株式会社 2017-08-29 CN disclosed
CN-103038258-B Compositions and methods of use for antibodies to treat low density lipoprotein-related protein 6(LRP6) 诺华股份有限公司 2017-02-15 CN disclosed
EP-3102611-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF Cangene Corporation (CA) 2016-12-14 EP disclosed
WO-2015113169-A1 HUMANIZED BETA-AMYLOID BINDING MOLECULES AND USES THEREOF CNJ HOLDINGS, INC. (CA) 2015-08-06 WO disclosed
CN-101918834-A Calibrator/control for simultaneous assay of proteins capable of complexing with one another ORTHO CLINICAL DIAGNOSTICS INC 2010-12-15 CN disclosed
EP-1292615-B1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH CORP (US) 2006-10-25 EP disclosed
US-6664066-B2 Mutant measles virus V protein; gene expression and engineering WYETH HOLDINGS CORPORATION 2003-12-16 US disclosed
US-20030206925-A1 MODIFIED MORBILLIVIRUS V PROTEINS WYETH HOLDINGS CORPORATION 2003-11-06 US disclosed
EP-0781295-A4 ASP B1 INSULIN ANALOGS LILLY CO ELI (US) 2001-08-29 EP disclosed
EP-0781295-A1 ASP B1 INSULIN ANALOGS ELI LILLY AND COMPANY (US) 1997-07-02 EP disclosed
WO-1996004307-A1 ASPB1 INSULIN ANALOGS ELI LILLY AND COMPANY (US) 1996-02-15 WO disclosed
US-4772480-A Method of controllingly aging edible material YAMANE AKIYOSHI (JP) 1988-09-20 US disclosed