Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.67 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16972788 | 0.90 | PPARG (0.71) | HTR2BLOXL2PPARGHTR3AAKR1B1 | |
| SCHEMBL16972870 | 0.89 | PPARG (0.74) | HTR2BPPARGMEN1TNKSCYP3A4 | |
| SCHEMBL16972770 | 0.87 | LOXL2 (0.64) | HTR2BLOXL2PPARGALDH1A1CYP3A4 | |
| SCHEMBL18417922 | 0.81 | HTR2B (1.00) | HTR2BCYP3A4HTR3A | |
| SCHEMBL16972796 | 0.80 | LOXL2 (0.58) | HTR2BLOXL2PPARGMEN1HPGD | |
| SCHEMBL29129664 | 0.79 | PPARG (0.70) | HTR2BLOXL2PPARGMEN1TNKS | |
| SCHEMBL27806527 | 0.79 | PPARG (0.71) | HTR2BPPARGALDH1A1CYP3A4HPGD | |
| SCHEMBL30335890 | 0.79 | PPARG (0.71) | HTR2BPPARGALDH1A1CYP3A4HPGD | |
| SCHEMBL7901121 | 0.77 | LOXL2 (0.71) | LOXL2MEN1TNKSALDH1A1CYP3A4 | |
| SCHEMBL3661429 | 0.77 | ALOX15 (0.72) | LOXL2PPARGALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015116460-A1 | 2-SUBSTITUTED-5-HYDROXY-4H-CHROMEN-4-ONES AS NOVEL LIGANDS FOR THE SEROTONIN RECEPTOR 2B (5-HT2B) | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2015-08-06 | — | — | WO | claimed |