Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391819 | 0.91 | NOS3 (0.37) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL6522882 | 0.88 | NOS3 (0.36) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL15361610 | 0.87 | SLC7A5 (0.38) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL9716084 | 0.85 | NOS3 (0.32) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL9716065 | 0.85 | NOS3 (0.32) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL103942 | 0.83 | SLC7A5 (0.43) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL17559246 | 0.83 | PTGS1 (0.41) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL1067388 | 0.82 | — | — | |
| SCHEMBL9139648 | 0.80 | SLC7A5 (0.41) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL8679965 | 0.80 | SLC7A5 (0.43) | NOS3NOS1NOS2SLC7A5SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000746-A1 | 11C-LABELLED PEPTIDE FOR DETECTING DISEASED TISSUE WHICH EXPRESSES A CHEMOKINE RECEPTOR | SIEMENS AKTIENGESELLSCHAFT (DE) | 2012-01-05 | — | — | WO | disclosed |