Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.30 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.30 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391819 | 0.97 | NOS3 (0.37) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL9139648 | 0.89 | SLC7A5 (0.41) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL103942 | 0.88 | SLC7A5 (0.43) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL1697281 | 0.88 | NOS3 (0.33) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL5704260 | 0.86 | NOS3 (0.36) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL15361610 | 0.85 | SLC7A5 (0.38) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL6389078 | 0.84 | PTGS1 (0.46) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL8695381 | 0.83 | NOS3 (0.38) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL2551500 | 0.80 | BHMT (0.38) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL6038226 | 0.79 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3387121-A1 | NOVEL PROTEINS FROM ANAEROBIC FUNGI AND USES THEREOF | The Regents of The University of California (US) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017100429-A1 | NOVEL PROTEINS FROM ANAEROBIC FUNGI AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-06-15 | — | — | WO | disclosed |
| US-20050186568-A1 | Kinases and phosphatases | INCYTE CORPORATION | 2005-08-25 | — | — | US | disclosed |
| WO-2003093434-A2 | NANOARCHAEUM NUCLEIC ACID MOLECULE | DIVERSA CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |