Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716084 | 1.00 | NOS3 (0.32) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| Glutamic Acid SCHEMBL9716070 | 0.92 | GRM8 (0.41) | — | |
| SCHEMBL5704260 | 0.89 | NOS3 (0.36) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| Alanine SCHEMBL9716094 | 0.86 | ALOX15 (0.39) | — | |
| SCHEMBL1697281 | 0.85 | NOS3 (0.33) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL7730688 | 0.83 | SLC7A5 (0.35) | NOS3NOS1NOS2SLC7A5 | |
| SCHEMBL15361610 | 0.82 | SLC7A5 (0.38) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL4409197 | 0.79 | SLC7A5 (0.33) | SLC7A5 | |
| SCHEMBL8679965 | 0.79 | SLC7A5 (0.43) | NOS3NOS1NOS2SLC7A5SLC1A5 | |
| SCHEMBL1537267 | 0.77 | SLC7A5 (0.41) | SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467972-A4 | RICKETTSIAL ANTIGENS FOR VACCINATION AND DIAGNOSIS | — | 1992-09-02 | — | — | EP | claimed |
| EP-0467972-A1 | RICKETTSIAL ANTIGENS FOR VACCINATION AND DIAGNOSIS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1992-01-29 | — | — | EP | claimed |
| WO-1990012030-A1 | RICKETTSIAL ANTIGENS FOR VACCINATION AND DIAGNOSIS | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 1990-10-18 | — | — | WO | claimed |