Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498488 | 0.76 | KDM4E (0.50) | KMT2APOLBLMNAMEN1ALDH1A1 | |
| SCHEMBL3219657 | 0.74 | POLB (0.44) | KMT2APOLBLMNAMEN1CFTR | |
| SCHEMBL5261044 | 0.74 | LMNA (0.44) | KMT2APOLBLMNAMEN1CFTR | |
| SCHEMBL6221726 | 0.74 | ADK (0.36) | KMT2APOLBLMNAMEN1CFTR | |
| SCHEMBL10533490 | 0.72 | ALDH1A1 (0.44) | KMT2APOLBLMNAMEN1ALDH1A1 | |
| SCHEMBL6702897 | 0.72 | POLB (0.42) | KMT2APOLBLMNAMEN1CFTR | |
| SCHEMBL18866755 | 0.72 | LMNA (0.42) | KMT2APOLBLMNAMEN1CFTR | |
| SCHEMBL31650964 | 0.69 | ALDH1A1 (0.56) | KMT2APOLBLMNAMEN1ALDH1A1 | |
| SCHEMBL10481123 | 0.69 | KDM4E (0.56) | KMT2APOLBLMNAMEN1ALDH1A1 | |
| SCHEMBL27535433 | 0.69 | KMT2A (0.40) | KMT2APOLBLMNAMEN1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10113052-B2 | 5H-furan-2-one derivatives stabilization of organic material | BASF SE (DE) | 2018-10-30 | — | — | US | disclosed |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | BASF SCHWEIZ AG (CH) | 2016-12-15 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| US-9458380-B2 | 5H-furan-2-one derivatives for stabilization of organic material | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| EP-2705082-B1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2015-09-23 | — | — | EP | disclosed |
| EP-2705082-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20140058021-A1 | 5H-Furan-2-one Derivatives for Stabilization of Organic Material | BASF SE (DE) | 2014-02-27 | — | — | US | disclosed |
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LTD. (IN) | 2013-05-16 | — | — | US | disclosed |
| WO-2012150527-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150527-A1 | 5H-FURAN-2-ONE DERIVATIVES FOR STABILIZATION OF ORGANIC MATERIAL | BASF SE (DE) | 2012-11-08 | — | — | WO | disclosed |
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123537-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | MYT1, TET1, LPXN | KMT2A 31/4885POLB 1055/4885LMNA 878/4885 |
| US-10113052-B2 | 5H-furan-2-one derivatives stabilization of organic material | C5, C9, CBR1 | KMT2A 3534/4885POLB 1203/4885LMNA 325/4885 |
| US-20160362535-A1 | 5H-FURAN-2-ONE DERIVATIVES STABILIZATION OF ORGANIC MATERIAL | C5, C9, CBR1 | KMT2A 3534/4885POLB 1203/4885LMNA 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.