SCHEMBL169738

SCHEMBL169738

Cc1cc(C(C)C)c(N)cc1N

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.53
GAA P10253 1/20 0.53
GFER P55789 1/20 0.53
CYP3A4 P08684 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 4/20 0.44
CYP1A2 P05177 1/20 0.44
ALOX15 P16050 1/20 0.44
CASP7 P55210 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TERT O14746 1/20 0.38
TDP1 Q9NUW8 3/20 0.37
CASP1 P29466 1/20 0.37
MAPT P10636 2/20 0.35
UHRF1 Q96T88 1/20 0.34
GABRA1 P14867 1/20 0.34
GABRB1 P18505 1/20 0.34
LMNA P02545 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3649606 0.90 POLB (0.59) POLBGAAGFERCYP3A4TSHR
SCHEMBL12289335 0.87 CYP3A4 (0.50) POLBGAAGFERCYP3A4TSHR
SCHEMBL25555727 0.87 POLB (0.61) POLBGAAGFERCYP3A4TSHR
SCHEMBL19840416 0.85 CYP3A4 (0.55) POLBGAAGFERCYP3A4TSHR
SCHEMBL117750 0.84 PTK2 (0.41) POLBGAAGFERCYP3A4TSHR
SCHEMBL832810 0.81 GAA (0.46) POLBGAAGFERCYP3A4TSHR
SCHEMBL20017590 0.80 GAA (0.44) POLBGAAGFERCYP3A4TSHR
SCHEMBL25725280 0.80 POLB (0.59) POLBGAAGFERCYP3A4TSHR
SCHEMBL14154831 0.79 POLB (0.40) POLBGAAGFERCYP3A4TSHR
SCHEMBL15927484 0.79 POLB (0.44) POLBGAAGFERCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2220034-B1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2015-12-23 EP claimed
US-8668986-B2 Aromatic aldimines and polyurethane compositions which contain aldimine SIKA TECHNOLOGY AG (CH) 2014-03-11 US claimed
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2010-10-07 US claimed
EP-2220034-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE Sika Technology AG (CH) 2010-08-25 EP claimed
WO-2009062985-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE SIKA TECHNOLOGY AG (CH) 2009-05-22 WO claimed
US-5736070-A COMPRISING A TITANATE OR ZIRCONATE-COATED COPPER POWDER, A RESOLE BINDER, A CHELATING AGENT TO PREVENT OXIDATION, AN ADHESION IMPROVER AND A CONDUCTIVITY IMPROVER TATSUTA ELECTRIC WIRE AND CABLE CO., LTD. (JP) 1998-04-07 US claimed
US-4604484-A WITH PROPYLENE IN PRESENCE OF ALUMINUM ANILIDE ETHYL CORPORATION (US) 1986-08-05 US claimed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US claimed
EP-3938416-B1 POLYURETHANE COATING COMPOSITIONS AND THEIR USE AS GEL COATS COVESTRO LLC (US) 2025-09-10 EP disclosed
US-20240376246-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-11-14 US disclosed
US-20240343941-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-10-17 US disclosed
EP-4402191-A1 ONE-POT PROCESS FOR THE PRODUCTION OF POLYCARBODIIMIDE CURED POLYMERS BASF SE (DE) 2024-07-24 EP disclosed
EP-4380990-A1 DUAL-CURE RESIN COMPOSITION COMPRISING URETDIONE-CONTAINING COMPOUND AND ITS USE IN 3D PRINTING BASF SE (DE) 2024-06-12 EP disclosed
CN-117980366-A One pot process for producing polycarbodiimide cured polymers 巴斯夫欧洲公司 2024-05-03 CN disclosed
US-4611045-A POLYURETHANES MODIFIED WITH CHAIN EXTENDERS ETHYL CORPORATION (US) 1986-09-09 US disclosed
US-4604484-A WITH PROPYLENE IN PRESENCE OF ALUMINUM ANILIDE ETHYL CORPORATION (US) 1986-08-05 US disclosed
US-4604484-A WITH PROPYLENE IN PRESENCE OF ALUMINUM ANILIDE ETHYL CORPORATION (US) 1986-08-05 US disclosed
EP-0177916-A1 Mono-tertiary-alkylated toluenediamine and derivatives AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-04-16 EP disclosed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US disclosed
US-4440952-A POLYURETHANE CHAIN EXTENDER ETHYL CORPORATION (US) 1984-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100255314-A1 AROMATIC ALDIMINES AND POLYURETHANE COMPOSITIONS WHICH CONTAIN ALDIMINE ODC1, DDC, SRM POLB 151/4885GAA 1814/4885GFER 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.