Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 7/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.46 |
| ▸ | CDC7 | O00311 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22249678 | 0.80 | ALDH1A1 (0.61) | PIM1CDC7CSNK2A1PIM3PIM2 | |
| SCHEMBL13509562 | 0.80 | HRH4 (0.41) | MAPTHPGDNPC1RAB9AATM | |
| SCHEMBL16974110 | 0.77 | PIM1 (0.39) | MAPTHPGDNPC1RAB9AATM | |
| SCHEMBL31485757 | 0.76 | PLA2G2A (0.42) | ATMPIM1CSNK2BCDC7CSNK2A2 | |
| SCHEMBL483929 | 0.75 | SMN1; SMN2 (0.51) | MAPTHPGDNPC1RAB9AKMT2A | |
| SCHEMBL22483135 | 0.75 | IDO1 (0.34) | KMT2AALDH1A1LMNAGPR55SMN1; SMN2 | |
| SCHEMBL15317423 | 0.75 | PIM1 (0.47) | MAPTHPGDNPC1RAB9AATM | |
| SCHEMBL16982232 | 0.74 | SMN1; SMN2 (0.35) | MAPTHPGDNPC1RAB9AKMT2A | |
| SCHEMBL22249679 | 0.73 | SMN1; SMN2 (0.36) | MAPTHPGDNPC1RAB9AKMT2A | |
| SCHEMBL22483138 | 0.73 | EGFR (0.39) | HPGDNPC1RAB9ACSNK2A1CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114102-A1 | SILYL SUBSTITUTED AZADIBENZOFURANS AND AZADIBENZOTHIOPHENES | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015114102-A1 | SILYL SUBSTITUTED AZADIBENZOFURANS AND AZADIBENZOTHIOPHENES | BASF SE (DE) | 2015-08-06 | — | — | WO | disclosed |