SCHEMBL15317423

SCHEMBL15317423

Brc1ccc2oc3cccnc3c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.47
CSNK2B P67870 3/20 0.47
CSNK2A2 P19784 2/20 0.47
PIM3 Q86V86 2/20 0.47
PIM2 Q9P1W9 2/20 0.47
CDC7 O00311 2/20 0.47
CSNK2A1 P68400 2/20 0.47
CSNK2A3 Q8NEV1 1/20 0.47
NPC1 O15118 5/20 0.42
RAB9A P51151 4/20 0.42
MAPT P10636 3/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL570295 0.87 KMT2A (0.47) PIM1CSNK2BCSNK2A2PIM3PIM2
SCHEMBL17705011 0.86 HTT (0.41) PIM1CSNK2BCSNK2A2PIM3PIM2
SCHEMBL15317424 0.85 GABRP (0.43) CSNK2BCSNK2A2CSNK2A1NPC1RAB9A
SCHEMBL18015362 0.81 CDC7 (0.36) PIM1CSNK2BCSNK2A2PIM3PIM2
SCHEMBL16305027 0.81 CA9 (0.36) PIM1CSNK2BCSNK2A2PIM3PIM2
SCHEMBL15835963 0.81 NPC1 (0.44) NPC1RAB9AMAPTHPGDKMT2A
SCHEMBL16482063 0.81 NPC1 (0.44) NPC1RAB9AMAPTHPGDKMT2A
SCHEMBL15835964 0.81 NPC1 (0.44) NPC1RAB9AMAPTHPGDKMT2A
SCHEMBL3661706 0.79 ALDH1A1 (0.54) PIM1CSNK2BCSNK2A2PIM3PIM2
SCHEMBL16482065 0.79 NPC1 (0.40) NPC1RAB9AMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11024815-B2 Metal complexes MERCK PATENT GMBH (DE) 2021-06-01 US disclosed
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
EP-3254317-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-07-31 EP disclosed
US-10153437-B2 Compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-12-11 US disclosed
US-9991447-B2 Material for organic electroluminescent element, and organic electroluminescent element produced using same IDEMITSU KOREA CO., LTD. (JP) 2018-06-05 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
EP-3318566-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC Ireland Limited (IE) 2018-05-09 EP disclosed
US-9960364-B2 Ladder compound, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-01 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
WO-2014057684-A1 LADDER COMPOUND, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 出光興産株式会社 (JP) 2014-04-17 WO disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
EP-2711363-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE Idemitsu Kosan Co., Ltd (JP) 2014-03-26 EP disclosed
EP-2660890-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2013-11-06 EP disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10153437-B2 Compound, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, LEF1, LAGE3 PIM1 157/4885CSNK2B 887/4885CSNK2A2 839/4885
US-11024815-B2 Metal complexes EXOC4, EXOC3, TIMCC PIM1 2799/4885CSNK2B 4238/4885CSNK2A2 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.