Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1E | P28566 | 2/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177706 | 0.86 | HTR1E (0.60) | HTR1ES1PR3TSHRCHRM3MEN1 | |
| SCHEMBL1177709 | 0.86 | HTR1E (0.60) | HTR1ES1PR3TSHRCHRM3MEN1 | |
| SCHEMBL5053665 | 0.84 | HTR1E (0.55) | HTR1ES1PR3TSHRSLC6A3CHRM3 | |
| SCHEMBL28181806 | 0.84 | HTR1E (0.58) | HTR1ES1PR3TSHRSLC6A3CHRM3 | |
| SCHEMBL5736102 | 0.84 | SLC6A3 (0.52) | HTR1ES1PR3SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7103544 | 0.84 | SLC6A2 (0.62) | HTR1ES1PR3TSHRSLC6A3SLC6A2 | |
| SCHEMBL27701362 | 0.83 | SLC6A3 (0.47) | HTR1ES1PR3SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9809565 | 0.82 | CHRM3 (0.61) | HTR1ES1PR3TSHRSLC6A3SLC6A2 | |
| SCHEMBL9154015 | 0.81 | SLC6A3 (0.65) | HTR1ES1PR3SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5746887 | 0.81 | HTR1E (0.63) | HTR1ES1PR3TSHRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096518-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-08-04 | — | — | US | disclosed |