Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16976492 | 0.90 | IDO1 (0.41) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL877030 | 0.84 | IDO1 (0.39) | IDO1FFAR2HDAC4P2RX7MAPT | |
| SCHEMBL9966553 | 0.81 | IDO1 (0.44) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL16976491 | 0.80 | HSD11B1 (0.37) | IDO1P2RX7HSD11B1 | |
| SCHEMBL9966332 | 0.79 | AKR1C1 (0.49) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL16602861 | 0.78 | HDAC1 (0.43) | FFAR2HDAC4P2RX7RAB9ASMN1; SMN2 | |
| SCHEMBL16441380 | 0.78 | LMNA (0.43) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL17796436 | 0.77 | IDO1 (0.48) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL15143204 | 0.77 | IDO1 (0.48) | IDO1FFAR2HDAC4P2RX7NAPRT | |
| SCHEMBL16976480 | 0.76 | ALOX5AP (0.46) | IDO1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619197-B1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2015-08-05 | — | — | EP | disclosed |