Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16976490 | 0.82 | ALOX5AP (0.49) | — | |
| SCHEMBL16602863 | 0.81 | THRB (0.38) | HSD11B1KMT2AMEN1 | |
| SCHEMBL16602731 | 0.81 | ALOX5AP (0.47) | IDO1 | |
| SCHEMBL16976489 | 0.80 | IDO1 (0.42) | HSD11B1IDO1P2RX7 | |
| SCHEMBL16976492 | 0.79 | IDO1 (0.41) | HSD11B1IDO1P2RX7KMT2AMEN1 | |
| SCHEMBL16602804 | 0.75 | ALOX5AP (0.47) | IDO1 | |
| SCHEMBL16602712 | 0.75 | ALOX5AP (0.47) | IDO1 | |
| SCHEMBL17799093 | 0.74 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL17799100 | 0.74 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL877030 | 0.74 | IDO1 (0.39) | IDO1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619197-B1 | OXADIAZOLE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2015-08-05 | — | — | EP | disclosed |