Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15195988 | 0.90 | ALDH1A1 (0.61) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL9643594 | 0.84 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL496753 | 0.82 | ALDH1A1 (0.61) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL16977970 | 0.77 | GABRA1 (0.40) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL10503140 | 0.76 | ALDH1A1 (0.53) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL11555907 | 0.73 | MAPT (0.50) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL10709819 | 0.72 | ALDH1A1 (0.59) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL29358687 | 0.72 | ALDH1A1 (1.00) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL50705 | 0.72 | ALDH1A1 (1.00) | ALDH1A1ALOX15HPGDHSD17B10TDP1 | |
| SCHEMBL11102519 | 0.72 | ESR1 (0.44) | ALDH1A1ALOX15HPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150217602-A1 | CORD RUBBERIZED IN SITU COMPRISING A COMPOSITION CONTAINING AN ORGANIC POLYSULPHIDE | COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) | 2015-08-06 | — | — | US | disclosed |