Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16572446 | 0.78 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL12879438 | 0.76 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL12879436 | 0.76 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL14325927 | 0.76 | KMT2A (0.43) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL15187872 | 0.74 | KMT2A (0.38) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL13484140 | 0.74 | KMT2A (0.38) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL13484108 | 0.74 | KMT2A (0.33) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL14325928 | 0.74 | KMT2A (0.36) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL12879442 | 0.70 | KMT2A (0.53) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL14413591 | 0.67 | KMT2A (0.42) | ALDH1A1MEN1KMT2AKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | LIFE TECHNOLOGIES CORP (US) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | ALDH1A1 341/4885MEN1 4693/4885KMT2A 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.