Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879436 | 0.88 | KMT2A (0.36) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL14325927 | 0.88 | KMT2A (0.43) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL16572446 | 0.88 | KMT2A (0.36) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL13484140 | 0.86 | KMT2A (0.38) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL14325928 | 0.83 | KMT2A (0.36) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL13484108 | 0.83 | KMT2A (0.33) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL15187872 | 0.81 | KMT2A (0.38) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL14413591 | 0.78 | KMT2A (0.42) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL16978115 | 0.76 | ALDH1A1 (0.34) | KMT2AMEN1USP2ALDH1A1GAA | |
| SCHEMBL11367407 | 0.74 | KMT2A (0.44) | KMT2AMEN1USP2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160334393-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | Life Technologies Corporation | 2016-11-17 | — | — | US | disclosed |
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | LIFE TECHNOLOGIES CORP (US) | 2015-08-06 | — | — | US | disclosed |
| US-8981100-B2 | Use of novel coumarins as glutathione and thiol labels | Life Technologies Corporation (US) | 2015-03-17 | — | — | US | disclosed |
| US-20110045503-A1 | The Use of Novel Coumarins as Glutathione and Thiol Labels | Life Technologies Corporation (US) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150219634-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | KMT2A 4686/4885MEN1 4693/4885USP2 1543/4885 |
| US-20160334393-A1 | Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | KMT2A 4686/4885MEN1 4693/4885USP2 1543/4885 |
| US-20110045503-A1 | The Use of Novel Coumarins as Glutathione and Thiol Labels | GSTP1, GSTK1, GSTA1 | KMT2A 4601/4885MEN1 4727/4885USP2 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.