SCHEMBL16979766

SCHEMBL16979766

Cc1cn([C@H]2CC(OP(=O)(O)OC[C@H]3O[C@@H](n4ccc(N)nc4=O)CC3OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)CC3O)[C@@H](COP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.66
▸ TERT O14746 2/20 0.60
▸ F2 P00734 1/20 0.53
▸ RNASEL Q05823 4/20 0.52
▸ P2RY2 P41231 2/20 0.51
▸ P2RY4 P51582 2/20 0.51
▸ P2RY6 Q15077 2/20 0.51
▸ POLB P06746 1/20 0.50
▸ ENPP1 P22413 1/20 0.48
▸ P2RY1 P47900 1/20 0.48
▸ TYMS P04818 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30632043 1.00 DTYMK (0.66) DTYMKTERTF2RNASELP2RY2
SCHEMBL16983788 1.00 DTYMK (0.66) DTYMKTERTF2RNASELP2RY2
SCHEMBL29401735 0.96 DTYMK (0.65) DTYMKTERTF2RNASELP2RY2
SCHEMBL30301232 0.96 DTYMK (0.65) DTYMKTERTF2RNASELP2RY2
SCHEMBL29774178 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2
SCHEMBL29359812 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2
SCHEMBL29503590 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2
SCHEMBL29923029 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2
SCHEMBL15127423 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2
SCHEMBL29429631 0.96 TERT (0.62) DTYMKTERTF2RNASELP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315537-B2 Multiple orthogonal labelling of oligonucleotides DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2016-04-19 — — US disclosed
US-20150218203-A1 MULTIPLE ORTHOGONAL LABELLING OF OLIGONUCLEOTIDES DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2015-08-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218203-A1 MULTIPLE ORTHOGONAL LABELLING OF OLIGONUCLEOTIDES RTCB, ADAR, POLN DTYMK 25/4885TERT 808/4885F2 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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