SCHEMBL29401735

SCHEMBL29401735

Cc1cn(C2CC(OP(=O)(O)OCC3OC(n4cnc5c(N)ncnc54)CC3O)C(COP(=O)(O)OC3CC(n4ccc(N)nc4=O)OC3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DTYMK P23919 4/20 0.65
▸ TERT O14746 2/20 0.59
▸ F2 P00734 1/20 0.57
▸ RNASEL Q05823 4/20 0.51
▸ P2RY2 P41231 3/20 0.50
▸ P2RY4 P51582 3/20 0.50
▸ P2RY6 Q15077 3/20 0.50
▸ POLB P06746 1/20 0.49
▸ ENPP1 P22413 1/20 0.47
▸ P2RY1 P47900 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30301232 1.00 DTYMK (0.65) DTYMKTERTF2RNASELP2RY2
SCHEMBL30632043 0.96 DTYMK (0.66) DTYMKTERTF2RNASELP2RY2
SCHEMBL16983788 0.96 DTYMK (0.66) DTYMKTERTF2RNASELP2RY2
SCHEMBL16979766 0.96 DTYMK (0.66) DTYMKTERTF2RNASELP2RY2
SCHEMBL14174120 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2
SCHEMBL29423008 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2
SCHEMBL14184947 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2
SCHEMBL32665846 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2
SCHEMBL29387073 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2
SCHEMBL29959672 0.96 F2 (0.64) DTYMKTERTF2RNASELP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026351-A1 COMPOSITIONS COMPRISING AN RNA GUIDE TARGETING TRAC AND USES THEREOF Arbor Biotechnologies, Inc. (US) 2024-01-25 — — US claimed
WO-2023075154-A1 METHOD FOR INACTIVATING GENE OF PORCINE ENDOGENOUS RETROVIRUS AND COMPOSITION THEREOF 주식회사 툴젠 2023-05-04 — — WO claimed
US-12630839-B2 Compositions for the treatment of Fabry disease SANGAMO THERAPEUTICS, INC. (US) 2026-05-19 — — US disclosed
EP-4696310-A2 METHODS AND COMPOSITIONS FOR MODULATION OF TAU PROTEINS Sangamo Therapeutics, Inc. (US) 2026-02-18 — — EP disclosed
EP-3860618-B1 COMPOSITIONS FOR TREATING TAUOPATHY SANGAMO THERAPEUTICS INC (US) 2026-02-04 — — EP disclosed
US-20260009038-A1 COMPOSITIONS AND METHODS RELATED TO NUCLEIC ACID SENSORS UNIV ARIZONA STATE (US) 2026-01-08 — — US disclosed
US-20260009027-A1 PRIME EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (PERT) THE BROAD INSTITUTE, INC. (US) 2026-01-08 — — US disclosed
EP-4667565-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF FABRY DISEASE Sangamo Therapeutics, Inc. (US) 2025-12-24 — — EP disclosed
US-12492411-B2 Gene editing of monogenic disorders in human hematopoietic stem cells—correction of X-linked agammaglobulinemia (XLA) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-09 — — US disclosed
EP-4652272-A1 PRIME EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (PERT) The Broad Institute Inc. (US) 2025-11-26 — — EP disclosed
US-20250313848-A1 ENGINEERED GENETIC MODULATORS SANGAMO THERAPEUTICS, INC. (US) 2025-10-09 — — US disclosed
US-11401512-B2 Engineered target specific nucleases SANGAMO THERAPEUTICS, INC. (US) 2022-08-02 — — US disclosed
US-20220175839-A1 TARGETED DISRUPTION OF THE MHC CELL RECEPTOR SANGAMO THERAPEUTICS INC (US) 2022-06-09 — — US disclosed
WO-2022119367-A1 TRANSGENIC ANIMAL HAVING MODIFIED MYOSTATIN GENE ㈜라트바이오 2022-06-09 — — WO disclosed
CN-108738326-B Novel CRISPR-associated transposase and use thereof 孟山都技术公司 2022-05-06 — — CN disclosed
CN-108024544-B Delivery methods and compositions for nuclease-mediated genome engineering 桑格摩生物治疗股份有限公司 2022-04-29 — — CN disclosed
US-11285175-B2 Targeted disruption of the MHC cell receptor SANGAMO THERAPEUTICS, INC. (US) 2022-03-29 — — US disclosed
EP-3964573-A1 ENGINEERED TARGET SPECIFIC NUCLEASES Sangamo Therapeutics, Inc. (US) 2022-03-09 — — EP disclosed
EP-3955916-A1 25-HYDROXYCHOLESTEROL (25HC), CRYAB AGGREGATION INHIBITOR, IS A NOVEL SENOLYTIC Buck Institute for Research on Aging (US) 2022-02-23 — — EP disclosed
EP-3946384-A1 METHODS FOR THE TREATMENT OF BETA-THALASSEMIA Sangamo Therapeutics, Inc. (US) 2022-02-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009027-A1 PRIME EDITING-MEDIATED READTHROUGH OF PREMATURE TERMINATION CODONS (PERT) NSUN3, UPF1, TRMT1L DTYMK 423/4885TERT 407/4885F2 3513/4885
US-20260009038-A1 COMPOSITIONS AND METHODS RELATED TO NUCLEIC ACID SENSORS ADAR, ADA, YARS1 DTYMK 105/4885TERT 1125/4885F2 4857/4885
US-11401512-B2 Engineered target specific nucleases ZFR, ZFX, HELZ DTYMK 25/4885TERT 2547/4885F2 3683/4885
US-12630839-B2 Compositions for the treatment of Fabry disease APOB, HBB, GLA DTYMK 3677/4885TERT 2736/4885F2 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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