Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127910 | 0.85 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL18740493 | 0.85 | ROCK2 (0.56) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL18740492 | 0.85 | ROCK2 (0.56) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL1285890 | 0.84 | ALDH1A1 (0.73) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL743064 | 0.84 | ALDH1A1 (0.73) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL1285869 | 0.84 | ALDH1A1 (0.73) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL18767128 | 0.83 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL18767077 | 0.82 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL18767075 | 0.81 | MAPT (0.57) | L3MBTL1ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL13229107 | 0.80 | ALDH1A1 (0.73) | ALDH1A1LMNANPC1POLBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160189-A1 | METHOD OF SCREENING FOR INHIBITORS OF sPLA2-IIA | SCOTT KIERAN (AU) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011160189-A1 | METHOD OF SCREENING FOR INHIBITORS OF sPLA2-IIA | SCOTT KIERAN (AU) | 2011-12-29 | — | — | WO | disclosed |