SCHEMBL743064

SCHEMBL743064

CC(NC(=O)c1ccccc1C(=O)O)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.73
KDM4E B2RXH2 5/20 0.73
HPGD P15428 4/20 0.73
HSD17B10 Q99714 3/20 0.73
LMNA P02545 2/20 0.73
POLB P06746 2/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
NPC1 O15118 1/20 0.57
MAPK8 P45983 1/20 0.56
KMT2A Q03164 1/20 0.56
HDAC3 O15379 1/20 0.55
HDAC4 P56524 1/20 0.55
HDAC1 Q13547 1/20 0.55
CNR1 P21554 1/20 0.55
CNR2 P34972 1/20 0.55
TSHR P16473 1/20 0.55
RECQL P46063 1/20 0.55
HDAC6 Q9UBN7 1/20 0.54
KCNA5 P22460 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285890 1.00 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL1285869 1.00 ALDH1A1 (0.73) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL16127910 0.90 ALDH1A1 (0.60) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL16088681 0.88 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL4930922 0.86 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL27651927 0.86 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL1698252 0.84 L3MBTL1 (0.58) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL16348943 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL20022689 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDHSD17B10LMNA
SCHEMBL12461860 0.84 ALDH1A1 (0.71) ALDH1A1KDM4EHPGDHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12551465-B2 Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition CELLTRION INC. (KR) 2026-02-17 US claimed
US-11760750-B1 Process for preparing levoketoconazole NURAY CHEMICALS PRIVATE LIMITED (IN) 2023-09-19 US claimed
US-20230190708-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION CELLTRION, INC. (KR) 2023-06-22 US claimed
US-20230122169-A1 NOVEL METHOD FOR PREPARING (-)-CIBENZOLINE SUCCINATE CELLTRION, INC. (KR) 2023-04-20 US claimed
EP-4140482-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION Celltrion, Inc. (KR) 2023-03-01 EP claimed
CN-113718256-B Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2022-11-11 CN claimed
US-20220162233-A1 PROCESSES AND COMPOUNDS RADIUS HEALTH, INC. 2022-05-26 US claimed
EP-3924328-A1 PROCESSES AND COMPOUNDS Radius Pharmaceuticals, Inc. (US) 2021-12-22 EP claimed
CN-113718256-A Copper etching liquid and application thereof in wafer level packaging 浙江奥首材料科技有限公司 2021-11-30 CN claimed
WO-2021215852-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION (주)셀트리온 (KR) 2021-10-28 WO claimed
US-20110124909-A1 NOVEL PROCESS GENERICS [UK] LIMITED (GB) 2011-05-26 US claimed
EP-2324009-A1 PROCESS FOR PREPARING CERTAIN CINNAMIDE COMPOUNDS Eisai R&D Management Co., Ltd. (JP) 2011-05-25 EP claimed
US-20110009629-A1 PREPARATION OF MORPHOLINE DERIVATIVES SANDOZ AG (CH) 2011-01-13 US claimed
EP-2262761-A1 NOVEL PROCESS Generics [UK] Limited (GB) 2010-12-22 EP claimed
EP-2260029-A1 PREPARATION OF MORPHOLINE DERIVATIVES Sandoz AG (CH) 2010-12-15 EP claimed
WO-2010131025-A1 SITAGLIPTIN SYNTHESIS GENERICS [UK] LIMITED (GB) 2010-11-18 WO claimed
WO-2010025197-A1 PROCESS FOR PREPARING CERTAIN CINNAMIDE COMPOUNDS EISAI R&D MANAGEMENT CO., LTD. (JP) 2010-03-04 WO claimed
WO-2009122215-A1 NOVEL PROCESS GENERICS [UK] LIMITED (GB) 2009-10-08 WO claimed
WO-2009106486-A1 PREPARATION OF MORPHOLINE DERIVATIVES SANDOZ AG (CH) 2009-09-03 WO claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009629-A1 PREPARATION OF MORPHOLINE DERIVATIVES OPRK1, TACR1, CMA1 ALDH1A1 1063/4885KDM4E 2781/4885HPGD 356/4885
US-12551465-B2 Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition ME2, TNNT2, TNNC1 ALDH1A1 440/4885KDM4E 1563/4885HPGD 213/4885
US-20230122169-A1 NOVEL METHOD FOR PREPARING (-)-CIBENZOLINE SUCCINATE SDHA, SDHB, ALDH5A1 ALDH1A1 230/4885KDM4E 1130/4885HPGD 256/4885
US-20110124909-A1 NOVEL PROCESS GABRE, GABRB2, GABRB1 ALDH1A1 1268/4885KDM4E 1978/4885HPGD 1801/4885
US-20220162233-A1 PROCESSES AND COMPOUNDS ESR1, ESR2, CYP19A1 ALDH1A1 546/4885KDM4E 520/4885HPGD 580/4885
US-20230190708-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION ATP2A2, CPT1B, TNNT2 ALDH1A1 1793/4885KDM4E 2539/4885HPGD 1156/4885
US-11760750-B1 Process for preparing levoketoconazole KHK, KYAT3, PLK3 ALDH1A1 2659/4885KDM4E 378/4885HPGD 2593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.