Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282091 | 0.84 | CYP1A2 (0.50) | ALDH1A1L3MBTL1MAPTNPSR1CYP1A2 | |
| SCHEMBL8693129 | 0.81 | MAPT (0.51) | L3MBTL1MAPTTDP1HTR2BHTR1A | |
| SCHEMBL9538824 | 0.80 | MAPT (0.41) | MAPTHTR2AHTR2BHTR1AHTR2C | |
| SCHEMBL93243 | 0.79 | CA1 (0.54) | ALDH1A1L3MBTL1CYP1A2TDP1SLC6A2 | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| 1,2-Diethoxybenzene SCHEMBL29428929 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL4607067 | 0.76 | HTR2C (0.53) | ALDH1A1L3MBTL1MAPTNPSR1GLA | |
| SCHEMBL28693925 | 0.75 | LMNA (0.33) | ALDH1A1CYP1A2ADRB2KDM4EALOX15 | |
| SCHEMBL7806133 | 0.73 | SLC6A4 (0.42) | L3MBTL1MAPTCYP2D6TDP1SLC6A2 | |
| SCHEMBL28355135 | 0.73 | HRH1 (0.47) | ALDH1A1L3MBTL1TDP1ADRB2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2558437-A2 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | Supernus Pharmaceuticals, Inc. (US) | 2013-02-20 | — | — | EP | claimed |
| WO-2011130194-A2 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | SUPERNUS PHARMACEUTICALS INC. (US) | 2011-10-20 | — | — | WO | claimed |
| EP-2558437-A2 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | Supernus Pharmaceuticals, Inc. (US) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011130194-A2 | METHODS FOR PRODUCING VILOXAZINE SALTS AND NOVEL POLYMORPHS THEREOF | SUPERNUS PHARMACEUTICALS INC. (US) | 2011-10-20 | — | — | WO | disclosed |