Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16982851 | 0.87 | KMT2A (0.56) | SMN1; SMN2HTTRAB9AKDM4EMEN1 | |
| SCHEMBL31224439 | 0.87 | KMT2A (0.56) | SMN1; SMN2HTTRAB9AKDM4EMEN1 | |
| SCHEMBL29450605 | 0.80 | ALDH1A1 (0.64) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL29450606 | 0.74 | KMT2A (0.65) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL9426325 | 0.72 | MAPT (0.60) | MAPTALDH1A1SMN1; SMN2HTTRAB9A | |
| SCHEMBL18354581 | 0.70 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9AKDM4ENPC1 | |
| SCHEMBL14082162 | 0.66 | GRM5 (0.57) | ALDH1A1SMN1; SMN2RAB9AKDM4EMEN1 | |
| SCHEMBL29450637 | 0.66 | POLB (0.64) | ALDH1A1SMN1; SMN2HTTRAB9AKDM4E | |
| SCHEMBL12925598 | 0.66 | KDM4E (0.52) | ALDH1A1SMN1; SMN2HTTRAB9AKDM4E | |
| SCHEMBL28785613 | 0.66 | HPGDS (0.58) | MAPTALDH1A1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280142-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-07 | — | — | US | claimed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | claimed |
| US-10280142-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-07 | — | — | US | disclosed |
| US-10280142-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-07 | — | — | US | disclosed |
| EP-3101004-B1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2018-12-05 | — | — | EP | disclosed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
| US-9908852-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9908852-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-06 | — | — | US | disclosed |
| US-9908852-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170001960-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-05 | — | — | US | disclosed |
| US-20170001960-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-05 | — | — | US | disclosed |
| US-20170001960-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-05 | — | — | US | disclosed |
| EP-3101004-A1 | BIPYRIDYL COMPOUND | Japan Science and Technology Agency (JP) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015115519-A1 | BIPYRIDYL COMPOUND | 独立行政法人科学技術振興機構 | 2015-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001960-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | MAPT 4692/4885ALDH1A1 1501/4885SMN1; SMN2 3447/4885 |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | MAPT 4692/4885ALDH1A1 1501/4885SMN1; SMN2 3447/4885 |
| US-10280142-B2 | Bipyridyl compound | CBR1, NR0B2, ERBB2 | MAPT 4692/4885ALDH1A1 1501/4885SMN1; SMN2 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.