SCHEMBL16983787

SCHEMBL16983787

Nc1ccn([C@H]2C[C@@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)C[C@H]3O)[C@@H](COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.59
▸ ENPP1 P22413 3/20 0.56
▸ P2RY1 P47900 1/20 0.56
▸ RNASEL Q05823 3/20 0.52
▸ P2RY2 P41231 2/20 0.52
▸ P2RY4 P51582 2/20 0.52
▸ P2RY6 Q15077 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665600 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL31606440 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL29420330 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL29540129 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL16979764 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL30839331 0.94 P2RY2 (0.57) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL23140717 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL23157150 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL23140716 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL30632043 0.91 DTYMK (0.66) POLBENPP1P2RY1RNASELP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016118877-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-07-28 — — WO disclosed
US-9315537-B2 Multiple orthogonal labelling of oligonucleotides DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2016-04-19 — — US disclosed
US-20150218203-A1 MULTIPLE ORTHOGONAL LABELLING OF OLIGONUCLEOTIDES DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2015-08-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150218203-A1 MULTIPLE ORTHOGONAL LABELLING OF OLIGONUCLEOTIDES RTCB, ADAR, POLN POLB 54/4885ENPP1 1207/4885P2RY1 3601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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