SCHEMBL29540129

SCHEMBL29540129

Nc1ccn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(N)ncnc54)O[C@@H]3COP(=O)(O)O)O2)c(=O)n1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 2/20 0.59
▸ ENPP1 P22413 3/20 0.56
▸ P2RY1 P47900 1/20 0.56
▸ RNASEL Q05823 3/20 0.52
▸ P2RY2 P41231 2/20 0.52
▸ P2RY4 P51582 2/20 0.52
▸ P2RY6 Q15077 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30665600 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL31606440 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL29420330 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL16979764 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL16983787 1.00 POLB (0.59) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL30839331 0.94 P2RY2 (0.57) POLBENPP1P2RY1RNASELP2RY2
SCHEMBL23140717 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL23157150 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL23140716 0.92 RNASEL (0.54) P2RY1RNASELP2RY2
SCHEMBL30632043 0.91 DTYMK (0.66) POLBENPP1P2RY1RNASELP2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125741-A1 Methods and Systems for Multiplex Gene Amplification from Ultra-Low DNA Input Amounts and Uses Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-07 — — US claimed
EP-4594508-A2 SLC26A4 REGULATORY ELEMENTS AND USES THEREOF Decibel Therapeutics, Inc. (US) 2025-08-06 — — EP claimed
US-12247200-B2 Compositions and methods for generating massively parallel nucleic acid sequencing libraries BIOO SCIENTIFIC CORPORATION (US) 2025-03-11 — — US claimed
WO-2024099575-A1 ARTIFICIAL NUCLEIC ACIDS FOR SITE-DIRECTED EDITING OF A TARGET RNA EBERHARD KARLS UNIVERSITÄT TÜBINGEN (DE) 2024-05-16 — — WO claimed
WO-2024073635-A2 SLC26A4 REGULATORY ELEMENTS AND USES THEREOF Decibel Therapeutics, Inc. (US) 2024-04-04 — — WO claimed
US-20220098640-A1 Methods and Systems for Multiplex Gene Amplification from Ultra-Low DNA Input Amounts and Uses Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-03-31 — — US claimed
WO-2026099341-A1 BIOCONTAINMENT OF UNWANTED ENGINEERED CELLS USING NON-NATURAL AMINO ACIDS SNIPR BIOME APS (DK) 2026-05-15 — — WO disclosed
US-20260125741-A1 Methods and Systems for Multiplex Gene Amplification from Ultra-Low DNA Input Amounts and Uses Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-05-07 — — US disclosed
US-20260109980-A1 RNA-GUIDED DNA INTEGRATION USING TN7-LIKE TRANSPOSONS UNIV COLUMBIA (US) 2026-04-23 — — US disclosed
US-20260110001-A1 RECOMBINANT TYPE I-F3 TRANSPOSON-ASSOCIATED CRISPR-CAS SYSTEMS AND METHODS OF USE UNIV NORTH CAROLINA STATE (US) 2026-04-23 — — US disclosed
US-20260104409-A1 NEXT-GENERATION SEQUENCING FOR PROTEIN MEASUREMENT SOMALOGIC OPERATING CO INC (US) 2026-04-16 — — US disclosed
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER APTAH BIO INC (US) 2026-03-26 — — US disclosed
US-20260057967-A1 METHOD FOR PREDICTING THE MELTING TEMPERATURE OF OLIGONUCLEOTIDE SEEGENE INC (KR) 2026-02-26 — — US disclosed
EP-4168578-A1 COMPOSITIONS AND METHODS FOR IN SITU SINGLE CELL ANALYSIS USING ENZYMATIC NUCLEIC ACID EXTENSION Nanostring Technologies, Inc. (US) 2023-04-26 — — EP disclosed
US-20230047776-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATIONS APTAH BIO, INC. 2023-02-16 — — US disclosed
WO-2023288111-A2 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR GENE EXPRESSION REGULATION APTAH BIO, INC. (US) 2023-01-19 — — WO disclosed
WO-2022243659-A1 DNAZYME DESIGN UNIVERSITY OF ESSEX ENTERPRISES LIMITED (GB) 2022-11-24 — — WO disclosed
WO-2022213153-A1 OLIGONUCLEOTIDES Hudson Institute of Medical Research (AU) 2022-10-13 — — WO disclosed
US-20220307050-A1 NON-VIRAL TRANSGENESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-09-29 — — US disclosed
US-20220098640-A1 Methods and Systems for Multiplex Gene Amplification from Ultra-Low DNA Input Amounts and Uses Thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2022-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085315-A1 POLYNUCLEOTIDE COMPOSITIONS AND METHODS FOR TREATMENT OF CANCER RPRD2, RTCB, UPF1 POLB 224/4885ENPP1 899/4885P2RY1 2805/4885
US-20260104409-A1 NEXT-GENERATION SEQUENCING FOR PROTEIN MEASUREMENT PABPC4, MAX, FUS POLB 1781/4885ENPP1 1212/4885P2RY1 461/4885
US-20260109980-A1 RNA-GUIDED DNA INTEGRATION USING TN7-LIKE TRANSPOSONS ZFR, LUC7L2, SLIRP POLB 428/4885ENPP1 3886/4885P2RY1 4387/4885
US-20260125741-A1 Methods and Systems for Multiplex Gene Amplification from Ultra-Low DNA Input Amounts and Uses Thereof DNMT3A, DCTD, POLL POLB 14/4885ENPP1 1917/4885P2RY1 1336/4885
US-20260057967-A1 METHOD FOR PREDICTING THE MELTING TEMPERATURE OF OLIGONUCLEOTIDE TPR, POLM, POLRMT POLB 53/4885ENPP1 1489/4885P2RY1 2531/4885
US-20260110001-A1 RECOMBINANT TYPE I-F3 TRANSPOSON-ASSOCIATED CRISPR-CAS SYSTEMS AND METHODS OF USE RNGTT, LUC7L2, MUS81 POLB 915/4885ENPP1 4031/4885P2RY1 4659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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