SCHEMBL16984048

SCHEMBL16984048

CC(=O)Oc1c(F)cc2c(c1F)Oc1c(cc(F)c(OC(C)=O)c1F)C21OC(=O)c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.56
LMNA P02545 6/20 0.56
MEN1 O00255 5/20 0.56
KMT2A Q03164 5/20 0.56
USP2 O75604 2/20 0.56
HTT P42858 2/20 0.56
ALDH1A1 P00352 2/20 0.56
TDP1 Q9NUW8 4/20 0.47
RECQL P46063 2/20 0.47
BLM P54132 2/20 0.47
ACE2 Q9BYF1 2/20 0.47
PRMT1 Q99873 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
THRB P10828 1/20 0.47
CDK2 P24941 1/20 0.47
CHAT P28329 1/20 0.47
BLVRB P30043 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
GNG2 P59768 1/20 0.45
GNB1 P62873 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16980204 0.95 MAPT (0.51) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL16984106 0.86 GSTP1 (0.44) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL16983993 0.81 CYP3A4 (0.45) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL16980190 0.80 GSTP1 (0.43) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL15358858 0.80 MEN1 (0.65) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL29532322 0.80 PRMT1 (0.65) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL17100061 0.80 PRMT1 (0.65) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL1942341 0.79 MEN1 (0.61) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL16984105 0.79 GSTP1 (0.42) MAPTLMNAMEN1KMT2AUSP2
SCHEMBL30378455 0.78 MAPT (0.66) MAPTLMNAMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11585819-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical VERSITECH LIMITED (CN) 2023-02-21 US disclosed
US-20210096142-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL VERSITECH LIMITED (CN) 2021-04-01 US disclosed
US-10877051-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical THE UNIVERSITY OF HONG KONG (CN) 2020-12-29 US disclosed
EP-3099680-B1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL UNIV HONG KONG (CN) 2020-08-12 EP disclosed
US-20150219676-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL VERSITECH LIMITED (CN) 2015-08-06 US disclosed
WO-2015113455-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL THE UNIVERSITY OF HONG KONG (CN) 2015-08-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11585819-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical SQOR, MT-ND4, COX6A1 MAPT 1109/4885LMNA 2985/4885MEN1 4228/4885
US-10877051-B2 Bistrifilate-based fluorogenic probes for detection of superoxide anion radical SQOR, MT-ND4, COX6A1 MAPT 1218/4885LMNA 3385/4885MEN1 4073/4885
US-20210096142-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL SQOR, MT-ND4, COX6A1 MAPT 1218/4885LMNA 3385/4885MEN1 4073/4885
US-20150219676-A1 BISTRIFILATE-BASED FLUOROGENIC PROBES FOR DETECTION OF SUPEROXIDE ANION RADICAL SQOR, MT-ND4, COX6A1 MAPT 1218/4885LMNA 3385/4885MEN1 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.