Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31114267 | 0.85 | GPR35 (0.44) | GPR35KDM4ENOD2MAOBMIF | |
| SCHEMBL12038288 | 0.85 | KDM4E (0.49) | KDM4EMAOBMEN1KMT2AF2 | |
| SCHEMBL12038303 | 0.80 | MAOB (0.40) | KDM4EMAOBMIFPFKFB3MAOA | |
| SCHEMBL13494173 | 0.80 | RAB9A (0.50) | KDM4EMEN1KMT2AHSD17B10ALDH1A1 | |
| SCHEMBL30267413 | 0.80 | MIF (0.60) | KDM4EMAOBMIFPFKFB3MAOA | |
| SCHEMBL591197 | 0.80 | MIF (0.60) | KDM4EMAOBMIFPFKFB3MAOA | |
| SCHEMBL13494164 | 0.79 | KDM4E (0.57) | GPR35KDM4ENOD2MAOBMIF | |
| SCHEMBL14039317 | 0.78 | KMT2A (0.45) | KDM4EMAOBMAOAMEN1KMT2A | |
| SCHEMBL14405916 | 0.78 | KDM4E (0.54) | GPR35KDM4ENOD2MAOBMIF | |
| SCHEMBL16985170 | 0.78 | MCL1 (0.49) | KDM4EMEN1KMT2AHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2021-11-16 | — | — | US | disclosed |
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | BECTON, DICKINSON AND COMPANY | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029017-A1 | Mono-chlorinated hydroxycoumarin conjugates | CLSPN, CLTC, HACD3 | GPR35 3783/4885KDM4E 2368/4885NOD2 1924/4885 |
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | MKI67, DCX, CDK7 | GPR35 3017/4885KDM4E 2525/4885NOD2 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.